Loading...
Chemical structure of ML254

GC75832

ML254

Also known as 5-[2-(3-fluorophenyl)ethynyl]-N-(3-methyloxetan-3-yl)pyridine-2-carboxamide

ML254 is a potent mGlu5 potentiator, with EC50 and pEC50 of 9·3 nM and 8·03 nM for rat mGlu5, respectively

ChemicalCAS1428630-86-7MW310.32FormulaC18H15FN2O2
CAS number
1428630-86-7
Molecular weight
310.32
Formula
C18H15FN2O2
Solubility
DMSO： 100 mg/mL (322·25 mM; Need ultrasonic)
InChIKey
YMYCVXPMSMNWEP-UHFFFAOYSA-N
Catalogue number
GC75832
Brand
GLPBIO
Computed properties PubChem CID 53382545 · XLogP 2.5 · TPSA 51.2 Ų · H-bond donors 1
XLogP
2.5
TPSA
51.2 Ų
H-bond donors
1
H-bond acceptors
4
Rotatable bonds
4
Heavy atoms
23

SMILES CC1(COC1)NC(=O)C2=NC=C(C=C2)C#CC3=CC(=CC=C3)F

Computed descriptors from PubChem (CID 53382545), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.