GC75830
YF-2 hydrochloride
Also known as N-[4-chloro-3-(trifluoromethyl)phenyl]-2-[2-(dimethylamino)ethoxy]-6-ethoxybenzamide;hydrochloride
YF-2 hydrochloride is a highly selective, blood-brain-barrier permeable histone acetyltransferase activator, acetylates H3 in the hippocampus, with EC50s of 2·75 μM, 29·04 μM and 49·31 μM for CBP, PCAF, and GCN5, respectively, shows no effect on HDAC
ChemicalCAS1312005-62-1MW467.31FormulaC20H23Cl2F3N2O3
- CAS number
- 1312005-62-1
- Molecular weight
- 467.31
- Formula
- C20H23Cl2F3N2O3
- Solubility
- DMSO： 100 mg/mL (213·99 mM; Need ultrasonic); H2O： 3·12 mg/mL (6·68 mM; ultrasonic and warming and heat to 60°C)
- InChIKey
- TZHNKFGAPXMLJS-UHFFFAOYSA-N
- Catalogue number
- GC75830
- Brand
- GLPBIO
Computed properties PubChem CID 71528814 · TPSA 50.8 Ų · H-bond donors 2 · H-bond acceptors 7
- TPSA
- 50.8 Ų
- H-bond donors
- 2
- H-bond acceptors
- 7
- Rotatable bonds
- 8
- Heavy atoms
- 30
SMILES CCOC1=C(C(=CC=C1)OCCN(C)C)C(=O)NC2=CC(=C(C=C2)Cl)C(F)(F)F.Cl
Computed descriptors from PubChem (CID 71528814), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il