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Chemical structure of LL-K12-18

GC75802

LL-K12-18

LL-K12-18 is a two-site molecular glue that enhances the protein-protein interaction of the CDK12-DDB1 complex, stabilizing the CDK12-DDB1 complex and promoting the degradation of cyclin K (EC50=0·37 nM)

ChemicalMW559.49FormulaC25H32Cl2N10O
CAS number
Molecular weight
559.49
Formula
C25H32Cl2N10O
Solubility
DMSO: 25 mg/mL (44·68 mM; ultrasonic and warming and heat to 60°C)
Catalogue number
GC75802
Brand
GLPBIO

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.