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Chemical structure of AB25583

GC75778

AB25583

Also known as N-[5-[(4-chlorophenyl)methoxy]-1,3,4-thiadiazol-2-yl]-4-(2-methoxyphenyl)pyridine-3-carboxamide

AB25583 is a Polθ helicase (Polθ-hel) small molecule inhibitor, with an IC50 value of 6 nM

ChemicalCAS2565637-94-5MW452.91FormulaC22H17ClN4O3S
CAS number
2565637-94-5
Molecular weight
452.91
Formula
C22H17ClN4O3S
Solubility
DMSO： 125 mg/mL (275·99 mM; Need ultrasonic)
InChIKey
NKBJFGOHTSTLNB-UHFFFAOYSA-N
Catalogue number
GC75778
Brand
GLPBIO
Computed properties PubChem CID 155342563 · XLogP 4.5 · TPSA 114 Ų · H-bond donors 1
XLogP
4.5
TPSA
114 Ų
H-bond donors
1
H-bond acceptors
7
Rotatable bonds
7
Heavy atoms
31

SMILES COC1=CC=CC=C1C2=C(C=NC=C2)C(=O)NC3=NN=C(S3)OCC4=CC=C(C=C4)Cl

Computed descriptors from PubChem (CID 155342563), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.