Loading...
Chemical structure of BIO-7488

GC75767

BIO-7488

Also known as 2-(1-methyl-2-oxabicyclo[2.1.1]hexan-4-yl)-N-(6-methylpyrazolo[1,5-a]pyrimidin-3-yl)-7-propan-2-yloxyimidazo[1,2-a]pyrimidine-6-carboxamide

BIO-7488 is a potent, selective, oral active and CNS-penetrant IRAK4 inhibitor with the IC50 of 0·6 nM and > 30 μM for IRAK4 and hERG, respectively

ChemicalCAS2573211-25-1MW447.49FormulaC23H25N7O3
CAS number
2573211-25-1
Molecular weight
447.49
Formula
C23H25N7O3
Solubility
DMSO： 2 mg/mL (4·47 mM; ultrasonic and warming and heat to 60°C)
InChIKey
DEQCXGYERMCXNL-UHFFFAOYSA-N
Catalogue number
GC75767
Brand
GLPBIO
Computed properties PubChem CID 155437283 · XLogP 2.3 · TPSA 108 Ų · H-bond donors 1
XLogP
2.3
TPSA
108 Ų
H-bond donors
1
H-bond acceptors
7
Rotatable bonds
5
Heavy atoms
33

SMILES CC1=CN2C(=C(C=N2)NC(=O)C3=CN4C=C(N=C4N=C3OC(C)C)C56CC(C5)(OC6)C)N=C1

Computed descriptors from PubChem (CID 155437283), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.