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Chemical structure of LH2-051

GC75751

LH2-051

Also known as 1-[2-(1H-indol-3-yl)ethyl]-6,7-dimethoxy-2-(oxan-4-ylmethyl)-3,4-dihydro-1H-isoquinoline

LH2-051 is a lysosome-enhancing lead compound, which promotes the lysosome biogenesis and the Aβ aggregate clearance through dopamine transporter-cyclin-dependent kinase 9-transcription factor EB (DAT-CDK9-TFEB) pathway

ChemicalCAS2358754-22-8MW434.57FormulaC27H34N2O3
CAS number
2358754-22-8
Molecular weight
434.57
Formula
C27H34N2O3
Solubility
DMSO： 100 mg/mL (230·11 mM; Need ultrasonic)
InChIKey
WBEFXEHFEBYZEJ-UHFFFAOYSA-N
Catalogue number
GC75751
Brand
GLPBIO
Computed properties PubChem CID 139399313 · XLogP 4.8 · TPSA 46.7 Ų · H-bond donors 1
XLogP
4.8
TPSA
46.7 Ų
H-bond donors
1
H-bond acceptors
4
Rotatable bonds
7
Heavy atoms
32

SMILES COC1=C(C=C2C(N(CCC2=C1)CC3CCOCC3)CCC4=CNC5=CC=CC=C54)OC

Computed descriptors from PubChem (CID 139399313), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.