GC75630
TGR5 Receptor Agonist 4
Also known as (2-methoxyphenyl)methyl (4S)-4-(6-chloro-3-pyridinyl)-6-methyl-2-oxo-1-[[(2R)-oxolan-2-yl]methyl]-3,4-dihydropyridine-5-carboxylate
TGR5 Receptor Agonist 4 is an agonist of Bile Acid Receptor (TGR5), with EC50 for hTGR5 and mTGR5 of 2 nM and 3 nM, respectively
ChemicalCAS1872436-42-4MW470.95FormulaC25H27ClN2O5
- CAS number
- 1872436-42-4
- Molecular weight
- 470.95
- Formula
- C25H27ClN2O5
- Solubility
- DMSO： 100 mg/mL (212·34 mM; Need ultrasonic)
- InChIKey
- AARPMDPNSORGBN-UXHICEINSA-N
- Catalogue number
- GC75630
- Brand
- GLPBIO
Computed properties PubChem CID 118694559 · XLogP 3.3 · TPSA 78 Ų · H-bond donors 0
- XLogP
- 3.3
- TPSA
- 78 Ų
- H-bond donors
- 0
- H-bond acceptors
- 6
- Rotatable bonds
- 8
- Heavy atoms
- 33
SMILES CC1=C([C@@H](CC(=O)N1C[C@H]2CCCO2)C3=CN=C(C=C3)Cl)C(=O)OCC4=CC=CC=C4OC
Computed descriptors from PubChem (CID 118694559), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il