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Chemical structure of VK-0214

GC75624

VK-0214

Also known as [4-[(3-benzyl-4-hydroxyphenyl)methyl]-3,5-dimethylphenoxy]methylphosphonic acid

VK-0214 is an agonist for thyroid beta receptor (TRβ), which ameliorates the X-linked adrenoleukodystrophy (X-ALD), through activation of ABCD2 expression and reduction of very long chain fatty acids (VLCFA) accumulation

ChemicalCAS852949-30-5MW412.42FormulaC23H25O5P
CAS number
852949-30-5
Molecular weight
412.42
Formula
C23H25O5P
Solubility
DMSO: 125 mg/mL (303·09 mM; Need ultrasonic)
InChIKey
GFJCILQBXUTOGN-UHFFFAOYSA-N
Catalogue number
GC75624
Brand
GLPBIO
Computed properties PubChem CID 15942270 · XLogP 4.4 · TPSA 87 Ų · H-bond donors 3
XLogP
4.4
TPSA
87 Ų
H-bond donors
3
H-bond acceptors
5
Rotatable bonds
7
Heavy atoms
29

SMILES CC1=CC(=CC(=C1CC2=CC(=C(C=C2)O)CC3=CC=CC=C3)C)OCP(=O)(O)O

Computed descriptors from PubChem (CID 15942270), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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