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Chemical structure of WT-TTR inhibitor 1

GC75508

WT-TTR inhibitor 1

Also known as (2Z)-2-[(2-chlorophenyl)methylidene]-[1,3]thiazolo[3,2-a]benzimidazol-1-one

WT-TTR inhibitor 1 (Compound 21) is a wild-type Transthyretin (WT-TTR) inhibitor with 29·05% inhibition at 100 μM

ChemicalCAS23983-05-3MW312.77FormulaC16H9ClN2OS
CAS number
23983-05-3
Molecular weight
312.77
Formula
C16H9ClN2OS
Solubility
DMSO: 4·76 mg/mL (15·22 mM; Need ultrasonic and warming)
InChIKey
LSMPFFSYANAQSU-ZROIWOOFSA-N
Catalogue number
GC75508
Brand
GLPBIO
Computed properties PubChem CID 689165 · XLogP 4.7 · TPSA 60.2 Ų · H-bond donors 0
XLogP
4.7
TPSA
60.2 Ų
H-bond donors
0
H-bond acceptors
3
Rotatable bonds
1
Heavy atoms
21

SMILES C1=CC=C(C(=C1)/C=C\2/C(=O)N3C4=CC=CC=C4N=C3S2)Cl

Computed descriptors from PubChem (CID 689165), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.