Loading...
Chemical structure of JNK3 inhibitor-4

GC75464

JNK3 inhibitor-4

Also known as 2-[3-[2-[[(3S)-1-(cyclopropanecarbonyl)piperidin-3-yl]amino]pyrimidin-4-yl]-2-naphthalen-2-ylimidazol-4-yl]acetonitrile

JNK3 inhibitor-4 is a potent inhibitor of JNK3 (IC50=1·0 nM) based on 2-aryl-1-pyrimidinyl-1H-imidazole-5-yl acetonitrile

ChemicalCAS2409109-65-3MW477.56FormulaC28H27N7O
CAS number
2409109-65-3
Molecular weight
477.56
Formula
C28H27N7O
Solubility
DMSO： 100 mg/mL (209·40 mM; Need ultrasonic)
InChIKey
MIFPZJRPCSILQA-QHCPKHFHSA-N
Catalogue number
GC75464
Brand
GLPBIO
Computed properties PubChem CID 148488346 · XLogP 3.7 · TPSA 99.7 Ų · H-bond donors 1
XLogP
3.7
TPSA
99.7 Ų
H-bond donors
1
H-bond acceptors
6
Rotatable bonds
6
Heavy atoms
36

SMILES C1C[C@@H](CN(C1)C(=O)C2CC2)NC3=NC=CC(=N3)N4C(=CN=C4C5=CC6=CC=CC=C6C=C5)CC#N

Computed descriptors from PubChem (CID 148488346), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.