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Chemical structure of Autophagy-IN-1

GC75437

Autophagy-IN-1

Also known as tert-butyl N-[(3E,3aS,8bR)-3-[[(2R)-3,4-dimethyl-5-oxo-2H-furan-2-yl]oxymethylidene]-2-oxo-4,8b-dihydro-3aH-indeno[1,2-b]furan-7-yl]carbamate

Autophagy-IN-1 is a potent autophagy/mitophagy inhibitor, acts by selectively increasing the autophagic flux while blocking the autophagosome-lysosome fusion in cancer cells

ChemicalCAS3031485-19-2MW427.45FormulaC23H25NO7
CAS number
3031485-19-2
Molecular weight
427.45
Formula
C23H25NO7
Solubility
DMSO： 100 mg/mL (233·95 mM; Need ultrasonic)
InChIKey
RGNNYAWPIKPOLQ-PVBZKGQNSA-N
Catalogue number
GC75437
Brand
GLPBIO
Computed properties PubChem CID 164887505 · XLogP 2.7 · TPSA 100 Ų · H-bond donors 1
XLogP
2.7
TPSA
100 Ų
H-bond donors
1
H-bond acceptors
7
Rotatable bonds
5
Heavy atoms
31

SMILES CC1=C(C(=O)O[C@H]1O/C=C/2\[C@@H]3CC4=C([C@@H]3OC2=O)C=C(C=C4)NC(=O)OC(C)(C)C)C

Computed descriptors from PubChem (CID 164887505), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.