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Chemical structure of Ulimorelin

GC75397

Ulimorelin

Also known as (3R,6S,9R,12R)-6-cyclopropyl-12-[(4-fluorophenyl)methyl]-3,8,9-trimethyl-2-oxa-5,8,11,14-tetrazabicyclo[16.4.0]docosa-1(22),18,20-triene-7,10,13-trione

Ulimorelin (TZP-101) is a ghrelin receptor (GRLN) agonist with an EC50 of 29 nM and a Ki of 16 nM

ChemicalCAS842131-33-3MW538.65FormulaC30H39FN4O4
CAS number
842131-33-3
Molecular weight
538.65
Formula
C30H39FN4O4
Solubility
DMSO: ≥ 100 mg/mL (185·65 mM)
InChIKey
WGYPAJVJMXQXTR-ABNZCKJZSA-N
Catalogue number
GC75397
Brand
GLPBIO
Computed properties PubChem CID 11526696 · XLogP 3.8 · TPSA 99.8 Ų · H-bond donors 3
XLogP
3.8
TPSA
99.8 Ų
H-bond donors
3
H-bond acceptors
6
Rotatable bonds
3
Heavy atoms
39

SMILES C[C@@H]1CN[C@H](C(=O)N([C@@H](C(=O)N[C@@H](C(=O)NCCCC2=CC=CC=C2O1)CC3=CC=C(C=C3)F)C)C)C4CC4

Computed descriptors from PubChem (CID 11526696), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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