Loading...
Chemical structure of SJ1008030 TFA

GC75340

SJ1008030 TFA

Also known as 4-[[4-[1-[3-(cyanomethyl)-1-ethylsulfonylazetidin-3-yl]pyrazol-4-yl]-7H-pyrrolo[2,3-d]pyrimidin-2-yl]amino]-N-[2-[4-[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-5-yl]piperazin-1-yl]ethyl]benzamide;2,2,2-trifluoroacetic acid

SJ1008030 (compound 8) TFA is a JAK2 PROTAC which selectively degrades JAK2

ChemicalCAS2863634-97-1MW987.96FormulaC44H44F3N13O9S
CAS number
2863634-97-1
Molecular weight
987.96
Formula
C44H44F3N13O9S
Solubility
DMSO： 125 mg/mL (126·52 mM; Need ultrasonic)
InChIKey
RRJQTSMHAOAMTD-UHFFFAOYSA-N
Catalogue number
GC75340
Brand
GLPBIO
Computed properties PubChem CID 168475845 · TPSA 297 Ų · H-bond donors 5 · H-bond acceptors 20
TPSA
297 Ų
H-bond donors
5
H-bond acceptors
20
Rotatable bonds
13
Heavy atoms
70

SMILES CCS(=O)(=O)N1CC(C1)(CC#N)N2C=C(C=N2)C3=C4C=CNC4=NC(=N3)NC5=CC=C(C=C5)C(=O)NCCN6CCN(CC6)C7=CC8=C(C=C7)C(=O)N(C8=O)C9CCC(=O)NC9=O.C(=O)(C(F)(F)F)O

Computed descriptors from PubChem (CID 168475845), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.