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Chemical structure of Izuforant

GC75338

Izuforant

Also known as 1-(12-bromo-2,4,5,8,10-pentazatricyclo[7.4.0.02,6]trideca-1(9),3,5,7,10,12-hexaen-7-yl)-N-methylazetidin-3-amine

Izuforant (JW1601) (Compound 24) is an orally active histamine H4 receptor (H4R) antagonist with an IC50 of 36 nM against human H4R

ChemicalCAS1429374-83-3MW334.17FormulaC12H12BrN7
CAS number
1429374-83-3
Molecular weight
334.17
Formula
C12H12BrN7
Solubility
DMSO： 100 mg/mL (299·25 mM; ultrasonic and warming and heat to 60°C)
InChIKey
MMVBKZHQTLDYKG-UHFFFAOYSA-N
Catalogue number
GC75338
Brand
GLPBIO
Computed properties PubChem CID 71547284 · XLogP 1.4 · TPSA 71.2 Ų · H-bond donors 1
XLogP
1.4
TPSA
71.2 Ų
H-bond donors
1
H-bond acceptors
6
Rotatable bonds
2
Heavy atoms
20

SMILES CNC1CN(C1)C2=NC3=C(C=C(C=N3)Br)N4C2=NN=C4

Computed descriptors from PubChem (CID 71547284), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

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Documents
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