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Chemical structure of Caspase-3-IN-1

GC75214

Caspase-3-IN-1

Also known as 1-[(4-methoxyphenyl)methyl]-5-[(2S)-2-(pyridin-3-yloxymethyl)pyrrolidin-1-yl]sulfonylindole-2,3-dione

Caspase-3-IN-1 (compound 11b) is a potent Caspase-3 inhibitor, with an IC50 of 14·5 nM

ChemicalCAS872254-32-5MW507.56FormulaC26H25N3O6S
CAS number
872254-32-5
Molecular weight
507.56
Formula
C26H25N3O6S
Solubility
DMSO： 100 mg/mL (197·02 mM; Need ultrasonic)
InChIKey
XDHJBIYJRNFDKS-IBGZPJMESA-N
Catalogue number
GC75214
Brand
GLPBIO
Computed properties PubChem CID 11591540 · XLogP 2.7 · TPSA 114 Ų · H-bond donors 0
XLogP
2.7
TPSA
114 Ų
H-bond donors
0
H-bond acceptors
8
Rotatable bonds
8
Heavy atoms
36

SMILES COC1=CC=C(C=C1)CN2C3=C(C=C(C=C3)S(=O)(=O)N4CCC[C@H]4COC5=CN=CC=C5)C(=O)C2=O

Computed descriptors from PubChem (CID 11591540), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.