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Chemical structure of Tetomilast

GC74775

Tetomilast

Also known as 6-[2-(3,4-diethoxyphenyl)-1,3-thiazol-4-yl]pyridine-2-carboxylic acid

Tetomilast (OPC-6535) is a PDE4 inhibitor with potential for the research of inflammatory bowel disease (IBD) and chronic obstructive pulmonary disease (COPD)

ChemicalCAS145739-56-6MW370.42FormulaC19H18N2O4S
CAS number
145739-56-6
Molecular weight
370.42
Formula
C19H18N2O4S
Solubility
DMSO: 100 mg/mL (269·96 mM; Need ultrasonic)
InChIKey
XDBHURGONHZNJF-UHFFFAOYSA-N
Catalogue number
GC74775
Brand
GLPBIO
Computed properties PubChem CID 3025803 · XLogP 3.8 · TPSA 110 Ų · H-bond donors 1
XLogP
3.8
TPSA
110 Ų
H-bond donors
1
H-bond acceptors
7
Rotatable bonds
7
Heavy atoms
26

SMILES CCOC1=C(C=C(C=C1)C2=NC(=CS2)C3=NC(=CC=C3)C(=O)O)OCC

Computed descriptors from PubChem (CID 3025803), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.