Loading...
Chemical structure of Procaspase-3/6 activator 1

GC74748

Procaspase-3/6 activator 1

Also known as N-(3-imidazo[1,2-a]pyridin-2-ylphenyl)-8-methoxy-2-oxochromene-3-carboxamide

Procaspase-3/6 activator 1 (compound 1541) is a highly specific and robust activator of executioner procaspases-3 and -6, with EC50 values of 2·4 ± 0·2 and 2·8 ± 0·3 μM, respectively

ChemicalCAS1100353-03-4MW411.41FormulaC24H17N3O4
CAS number
1100353-03-4
Molecular weight
411.41
Formula
C24H17N3O4
Solubility
DMSO: 1 mg/mL (2·43 mM; ultrasonic and warming and heat to 60°C)
InChIKey
PQLVYQVWNPGJML-UHFFFAOYSA-N
Catalogue number
GC74748
Brand
GLPBIO
Computed properties PubChem CID 43816622 · XLogP 4.4 · TPSA 81.9 Ų · H-bond donors 1
XLogP
4.4
TPSA
81.9 Ų
H-bond donors
1
H-bond acceptors
5
Rotatable bonds
4
Heavy atoms
31

SMILES COC1=CC=CC2=C1OC(=O)C(=C2)C(=O)NC3=CC=CC(=C3)C4=CN5C=CC=CC5=N4

Computed descriptors from PubChem (CID 43816622), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.