Loading...
Chemical structure of Targefrin

GC74367

Targefrin

Also known as (3S)-3-[[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-3-(4-aminophenyl)-2-[(2-piperazin-1-ylacetyl)amino]propanoyl]amino]-4-methylpentanoyl]amino]propanoyl]amino]-3-[4-[2-(trifluoromethyl)phenyl]phenyl]propanoyl]pyrrolidine-2-carbonyl]amino]-4-[[(2S)-1-[[(1S)-2-[(2S)-2-[[(2S)-1-[[(2S)-5-carbamimidamido-1-[(2S)-2-carbamoylpyrrolidin-1-yl]-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]carbamoyl]pyrrolidin-1-yl]-1-cyclohexyl-2-oxoethyl]amino]-1-oxopropan-2-yl]amino]-4-oxobutanoic acid

Targefrin is a potent EphA2-targeting agent, acts as an antagonist

ChemicalCAS3031514-44-7MW1700.94FormulaC85H116F3N19O15
CAS number
3031514-44-7
Molecular weight
1700.94
Formula
C85H116F3N19O15
Solubility
DMSO ： 100 mg/mL (58·79 mM; Need ultrasonic)
InChIKey
UUKDZYHYHXLKTO-LMEGGTDHSA-N
Catalogue number
GC74367
Brand
GLPBIO
Computed properties PubChem CID 167312253 · XLogP 2.4 · TPSA 506 Ų · H-bond donors 16
XLogP
2.4
TPSA
506 Ų
H-bond donors
16
H-bond acceptors
22
Rotatable bonds
40
Heavy atoms
122

SMILES C[C@@H](C(=O)N[C@@H](CC1=CC=C(C=C1)C2=CC=CC=C2C(F)(F)F)C(=O)N3CCC[C@H]3C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](C)C(=O)N[C@@H](C4CCCCC4)C(=O)N5CCC[C@H]5C(=O)N[C@@H](CC6=CC=CC=C6)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N7CCC[C@H]7C(=O)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC8=CC=C(C=C8)N)NC(=O)CN9CCNCC9

Computed descriptors from PubChem (CID 167312253), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.