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Chemical structure of Glp-Asn-Pro-AMC

GC74329

Glp-Asn-Pro-AMC

Also known as (2S)-N-[(2S)-4-amino-1-[(2S)-2-[(4-methyl-2-oxochromen-7-yl)carbamoyl]pyrrolidin-1-yl]-1,4-dioxobutan-2-yl]-5-oxopyrrolidine-2-carboxamide

Glp-Asn-Pro-AMC is an inhibitor of trotropin-releasing hormone degrading enzyme (TRH-DE) with a Ki value of 0·97 μM

ChemicalCAS291752-43-7MW497.5FormulaC24H27N5O7
CAS number
291752-43-7
Molecular weight
497.5
Formula
C24H27N5O7
Solubility
DMSO : ≥ 125 mg/mL (251·26 mM)
InChIKey
YSNGYDACLOQMCZ-ULQDDVLXSA-N
Catalogue number
GC74329
Brand
GLPBIO
Computed properties PubChem CID 10255308 · XLogP -1.3 · TPSA 177 Ų · H-bond donors 4
XLogP
-1.3
TPSA
177 Ų
H-bond donors
4
H-bond acceptors
7
Rotatable bonds
7
Heavy atoms
36

SMILES CC1=CC(=O)OC2=C1C=CC(=C2)NC(=O)[C@@H]3CCCN3C(=O)[C@H](CC(=O)N)NC(=O)[C@@H]4CCC(=O)N4

Computed descriptors from PubChem (CID 10255308), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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