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Chemical structure of Spliceostatin A

GC74082

Spliceostatin A

Also known as [(Z,2S)-5-[[(2R,3R,5S,6S)-6-[(2E,4E)-5-[(3R,4R,5R,7S)-4-hydroxy-7-methoxy-7-methyl-1,6-dioxaspiro[2.5]octan-5-yl]-3-methylpenta-2,4-dienyl]-2,5-dimethyloxan-3-yl]amino]-5-oxopent-3-en-2-yl] acetate

Spliceostatin A, the FR901464 metlated derivative, is a potent anti-tumor agent

ChemicalCAS391611-36-2MW521.64FormulaC28H43NO8
CAS number
391611-36-2
Molecular weight
521.64
Formula
C28H43NO8
InChIKey
XKSGIJNRMWHQIQ-CGPJBNNXSA-N
Catalogue number
GC74082
Brand
GLPBIO
Computed properties PubChem CID 10673568 · XLogP 2.6 · TPSA 116 Ų · H-bond donors 2
XLogP
2.6
TPSA
116 Ų
H-bond donors
2
H-bond acceptors
8
Rotatable bonds
10
Heavy atoms
37

SMILES C[C@H]1C[C@H]([C@H](O[C@H]1C/C=C(\C)/C=C/[C@@H]2[C@H]([C@@]3(C[C@@](O2)(C)OC)CO3)O)C)NC(=O)/C=C\[C@H](C)OC(=O)C

Computed descriptors from PubChem (CID 10673568), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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