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Chemical structure of Pebezertinib

GC74071

Pebezertinib

Also known as N-[4-fluoro-3-[[2-[(1-methylpyrazol-4-yl)amino]-5-[4-(trifluoromethyl)phenyl]pyrimidin-4-yl]amino]phenyl]prop-2-enamide

Pebezertinib (BLU 451) is an orally active inhibitor for EGFR

ChemicalCAS2769954-39-2MW497.45FormulaC24H19F4N7O
CAS number
2769954-39-2
Molecular weight
497.45
Formula
C24H19F4N7O
Solubility
DMSO ： 116·67 mg/mL (234·54 mM; Need ultrasonic)
InChIKey
XIMJCWSFLXXQMZ-UHFFFAOYSA-N
Catalogue number
GC74071
Brand
GLPBIO
Computed properties PubChem CID 163280903 · XLogP 4.6 · TPSA 96.8 Ų · H-bond donors 3
XLogP
4.6
TPSA
96.8 Ų
H-bond donors
3
H-bond acceptors
10
Rotatable bonds
7
Heavy atoms
36

SMILES CN1C=C(C=N1)NC2=NC=C(C(=N2)NC3=C(C=CC(=C3)NC(=O)C=C)F)C4=CC=C(C=C4)C(F)(F)F

Computed descriptors from PubChem (CID 163280903), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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