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Chemical structure of BIIB129

GC74040

BIIB129

Also known as N-methyl-N-[3-methyl-3-[6-(1-methylpyrazol-4-yl)pyrazolo[1,5-a]pyrazin-4-yl]oxycyclobutyl]prop-2-enamide

BIIB129 is a covalent, selective, small molecule inhibitor of Bruton's tyrosine kinase (BTK) capable of penetrating the blood-brain barrier

ChemicalCAS2770960-52-4MW366.42FormulaC19H22N6O2
CAS number
2770960-52-4
Molecular weight
366.42
Formula
C19H22N6O2
Solubility
DMSO ： 100 mg/mL (272·91 mM; Need ultrasonic)
InChIKey
WBFSPPPOPIJCLF-UHFFFAOYSA-N
Catalogue number
GC74040
Brand
GLPBIO
Computed properties PubChem CID 163301394 · XLogP 1.2 · TPSA 77.6 Ų · H-bond donors 0
XLogP
1.2
TPSA
77.6 Ų
H-bond donors
0
H-bond acceptors
5
Rotatable bonds
5
Heavy atoms
27

SMILES CC1(CC(C1)N(C)C(=O)C=C)OC2=NC(=CN3C2=CC=N3)C4=CN(N=C4)C

Computed descriptors from PubChem (CID 163301394), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.