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Chemical structure of W6134

GC74028

W6134

Also known as N-[2-[2-chloro-4-[[2-(4-ethylsulfonylphenyl)acetyl]amino]phenyl]phenyl]prop-2-enamide

W6134 is highly potent and selective RORγ covalent inhibitor with IC50 of 0·21 μM

ChemicalCAS2983540-55-0MW482.98FormulaC25H23ClN2O4S
CAS number
2983540-55-0
Molecular weight
482.98
Formula
C25H23ClN2O4S
Solubility
DMSO ： 83·33 mg/mL (172·53 mM; Need ultrasonic)
InChIKey
PSNSGPNLXRHGNN-UHFFFAOYSA-N
Catalogue number
GC74028
Brand
GLPBIO
Computed properties PubChem CID 171378280 · XLogP 4.3 · TPSA 101 Ų · H-bond donors 2
XLogP
4.3
TPSA
101 Ų
H-bond donors
2
H-bond acceptors
4
Rotatable bonds
8
Heavy atoms
33

SMILES CCS(=O)(=O)C1=CC=C(C=C1)CC(=O)NC2=CC(=C(C=C2)C3=CC=CC=C3NC(=O)C=C)Cl

Computed descriptors from PubChem (CID 171378280), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.