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Chemical structure of DNA-PK-IN-12

GC74026

DNA-PK-IN-12

Also known as 7-methyl-2-[[4-methyl-6-(1-methylpyrazol-4-yl)-3-pyridinyl]amino]-9-(oxan-4-yl)purin-8-one

DNA-PK-IN-12 (compound 31t) is an oral active DNA-PK inhibitor with the IC50 of 0·1 nM

ChemicalCAS2792146-91-7MW420.47FormulaC21H24N8O2
CAS number
2792146-91-7
Molecular weight
420.47
Formula
C21H24N8O2
Solubility
DMSO ： 2 mg/mL (4·76 mM; ultrasonic and warming and heat to 60°C)
InChIKey
GDKSDPBBGUPQCM-UHFFFAOYSA-N
Catalogue number
GC74026
Brand
GLPBIO
Computed properties PubChem CID 164544735 · XLogP 1.1 · TPSA 101 Ų · H-bond donors 1
XLogP
1.1
TPSA
101 Ų
H-bond donors
1
H-bond acceptors
7
Rotatable bonds
4
Heavy atoms
31

SMILES CC1=CC(=NC=C1NC2=NC=C3C(=N2)N(C(=O)N3C)C4CCOCC4)C5=CN(N=C5)C

Computed descriptors from PubChem (CID 164544735), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.