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Chemical structure of CK-963

GC73987

CK-963

Also known as N-[6-[(3R,5R)-3,5-dimethylpiperidin-1-yl]-3-pyridinyl]-2-methyl-7-(2-morpholin-4-ylethoxy)-4-oxo-3H-quinazoline-6-sulfonamide

CK-963 is an activator for cardiac troponin (cTnC) with Ki of 11·5 μM

ChemicalCAS2851991-63-2MW556.68FormulaC27H36N6O5S
CAS number
2851991-63-2
Molecular weight
556.68
Formula
C27H36N6O5S
Solubility
DMSO ： 100 mg/mL (179·64 mM; Need ultrasonic)
InChIKey
PWDGOAJDNRTIMX-RTBURBONSA-N
Catalogue number
GC73987
Brand
GLPBIO
Computed properties PubChem CID 166007476 · XLogP 2 · TPSA 134 Ų · H-bond donors 2
XLogP
2
TPSA
134 Ų
H-bond donors
2
H-bond acceptors
10
Rotatable bonds
8
Heavy atoms
39

SMILES C[C@@H]1C[C@H](CN(C1)C2=NC=C(C=C2)NS(=O)(=O)C3=C(C=C4C(=C3)C(=O)NC(=N4)C)OCCN5CCOCC5)C

Computed descriptors from PubChem (CID 166007476), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.