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Chemical structure of CDK2-IN-23

GC73976

CDK2-IN-23

Also known as 1-[4-[2-[(1-cyclopropylsulfonylpiperidin-4-yl)amino]-5-(trifluoromethyl)pyrimidin-4-yl]pyrazol-1-yl]-2-methylpropan-2-ol

CDK2-IN-23 (Compound 17) is a kinase selective and highly potent CDK2 inhibitor (IC50 = 0·29 nM)

ChemicalCAS2488073-20-5MW488.53FormulaC20H27F3N6O3S
CAS number
2488073-20-5
Molecular weight
488.53
Formula
C20H27F3N6O3S
Solubility
DMSO : 100 mg/mL (204·70 mM; Need ultrasonic)
InChIKey
HTBKVAJZYRVZSW-UHFFFAOYSA-N
Catalogue number
GC73976
Brand
GLPBIO
Computed properties PubChem CID 155688637 · XLogP 1.6 · TPSA 122 Ų · H-bond donors 2
XLogP
1.6
TPSA
122 Ų
H-bond donors
2
H-bond acceptors
11
Rotatable bonds
7
Heavy atoms
33

SMILES CC(C)(CN1C=C(C=N1)C2=NC(=NC=C2C(F)(F)F)NC3CCN(CC3)S(=O)(=O)C4CC4)O

Computed descriptors from PubChem (CID 155688637), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.