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Chemical structure of PTK7/β-catenin-IN-6

GC73876

PTK7/β-catenin-IN-6

Also known as N-(3,4-dichlorophenyl)-2-[3-oxo-1-[(E)-3-phenylprop-2-enoyl]-2,4-dihydroquinoxalin-2-yl]acetamide

PTK7/β-catenin-IN-6 (Compound 03653) is an inhibitor for PTK7/β-catenin interaction, which inhibits the Wnt signaling pathway, and exhibits an anticancer activity against colorectal cancer (CRC)

ChemicalCAS1219439-82-3MW480.34FormulaC25H19Cl2N3O3
CAS number
1219439-82-3
Molecular weight
480.34
Formula
C25H19Cl2N3O3
Solubility
DMSO : 73·33 mg/mL (152·66 mM; Need ultrasonic)
InChIKey
VZIQATUWSFFKSJ-JLHYYAGUSA-N
Catalogue number
GC73876
Brand
GLPBIO
Computed properties PubChem CID 44615416 · XLogP 4.4 · TPSA 78.5 Ų · H-bond donors 2
XLogP
4.4
TPSA
78.5 Ų
H-bond donors
2
H-bond acceptors
3
Rotatable bonds
5
Heavy atoms
33

SMILES C1=CC=C(C=C1)/C=C/C(=O)N2C(C(=O)NC3=CC=CC=C32)CC(=O)NC4=CC(=C(C=C4)Cl)Cl

Computed descriptors from PubChem (CID 44615416), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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