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Chemical structure of VVD-214

GC73790

VVD-214

Also known as N-[(E,1S)-1-cyclopropyl-3-methylsulfonylprop-2-enyl]-2-(1,1-difluoroethyl)-4-phenoxypyrimidine-5-carboxamide

VVD-214 is a synthetic lethal allosteric inhibitor of WRN helicase

ChemicalCAS3026500-20-6MW437.46FormulaC20H21F2N3O4S
CAS number
3026500-20-6
Molecular weight
437.46
Formula
C20H21F2N3O4S
Solubility
DMSO : 100 mg/mL (228·59 mM; Need ultrasonic)
InChIKey
UWPFUBNCDABUEE-SIFUEBAJSA-N
Catalogue number
GC73790
Brand
GLPBIO
Computed properties PubChem CID 170717998 · XLogP 2.5 · TPSA 107 Ų · H-bond donors 1
XLogP
2.5
TPSA
107 Ų
H-bond donors
1
H-bond acceptors
8
Rotatable bonds
8
Heavy atoms
30

SMILES CC(C1=NC=C(C(=N1)OC2=CC=CC=C2)C(=O)N[C@H](/C=C/S(=O)(=O)C)C3CC3)(F)F

Computed descriptors from PubChem (CID 170717998), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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