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Chemical structure of NST-628

GC73789

NST-628

Also known as 3-[[3-fluoro-2-(methylsulfamoylamino)-4-pyridinyl]methyl]-7-[(3-fluoro-2-pyridinyl)oxy]-4-methylchromen-2-one

NST-628 is a brain-permeable MAPK pathway molecule glue that inhibits RAF phosphorylation and MEK activation

ChemicalCAS3002056-30-3MW488.46FormulaC22H18F2N4O5S
CAS number
3002056-30-3
Molecular weight
488.46
Formula
C22H18F2N4O5S
Solubility
DMSO ： ≥ 100 mg/mL (204·73 mM)
InChIKey
YQSZJOABXRROQR-UHFFFAOYSA-N
Catalogue number
GC73789
Brand
GLPBIO
Computed properties PubChem CID 169262739 · XLogP 2.7 · TPSA 128 Ų · H-bond donors 2
XLogP
2.7
TPSA
128 Ų
H-bond donors
2
H-bond acceptors
11
Rotatable bonds
7
Heavy atoms
34

SMILES CC1=C(C(=O)OC2=C1C=CC(=C2)OC3=C(C=CC=N3)F)CC4=C(C(=NC=C4)NS(=O)(=O)NC)F

Computed descriptors from PubChem (CID 169262739), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.