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Chemical structure of DEG-77

GC73741

DEG-77

Also known as N-[2-(2,6-dioxopiperidin-3-yl)-1-oxo-3H-isoindol-5-yl]-8-methoxy-2H-chromene-3-carboxamide

DEG-77, a PROTAC based IKZF2 and CK1α degrader, possesses suitable pharmacokinetic properties, solubility, and selectivity for in vivo studies (t1/2=8h)

ChemicalCAS3032265-06-5MW447.44FormulaC24H21N3O6
CAS number
3032265-06-5
Molecular weight
447.44
Formula
C24H21N3O6
Solubility
DMSO ： 50 mg/mL (111·75 mM; Need ultrasonic (<80°C))
InChIKey
ZFAKJMUJUNDGEI-UHFFFAOYSA-N
Catalogue number
GC73741
Brand
GLPBIO
Computed properties PubChem CID 169494265 · XLogP 1 · TPSA 114 Ų · H-bond donors 2
XLogP
1
TPSA
114 Ų
H-bond donors
2
H-bond acceptors
6
Rotatable bonds
4
Heavy atoms
33

SMILES COC1=CC=CC2=C1OCC(=C2)C(=O)NC3=CC4=C(C=C3)C(=O)N(C4)C5CCC(=O)NC5=O

Computed descriptors from PubChem (CID 169494265), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.