GC73684
CHK-336
Also known as 2-[5-(cyclopropylmethyl)-3-(4-fluorophenyl)-4-[(3-fluoro-4-sulfamoylphenyl)methyl]pyrazol-1-yl]-1,3-thiazole-4-carboxylic acid
CHK-336 (Example 1) is an orally active LDHA inhibitor (IC50＜1 nM) that inhibits lactate production in mouse hepatocytes
ChemicalCAS2743436-86-2MW530.57FormulaC24H20F2N4O4S2
- CAS number
- 2743436-86-2
- Molecular weight
- 530.57
- Formula
- C24H20F2N4O4S2
- Solubility
- DMSO ： ≥ 130 mg/mL (245·02 mM)
- InChIKey
- XAHAUTPHLZAEKK-UHFFFAOYSA-N
- Catalogue number
- GC73684
- Brand
- GLPBIO
Computed properties PubChem CID 162358463 · XLogP 4.9 · TPSA 165 Ų · H-bond donors 2
- XLogP
- 4.9
- TPSA
- 165 Ų
- H-bond donors
- 2
- H-bond acceptors
- 10
- Rotatable bonds
- 8
- Heavy atoms
- 36
SMILES C1CC1CC2=C(C(=NN2C3=NC(=CS3)C(=O)O)C4=CC=C(C=C4)F)CC5=CC(=C(C=C5)S(=O)(=O)N)F
Computed descriptors from PubChem (CID 162358463), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il