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Chemical structure of STX-478

GC73682

STX-478

Also known as 1-(2-aminopyrimidin-5-yl)-3-[(1R)-1-(5,7-difluoro-3-methyl-1-benzofuran-2-yl)-2,2,2-trifluoroethyl]urea

STX-478 (compound 80) is an oral CNS-penetrant allosteric mutant-selective PI3Kα inhibitor

ChemicalCAS2883540-92-7MW401.29FormulaC16H12F5N5O2
CAS number
2883540-92-7
Molecular weight
401.29
Formula
C16H12F5N5O2
Solubility
DMSO ： 200 mg/mL (498·39 mM; Need ultrasonic)
InChIKey
LGPNQALKGDDVBD-CYBMUJFWSA-N
Catalogue number
GC73682
Brand
GLPBIO
Computed properties PubChem CID 166532451 · XLogP 2.5 · TPSA 106 Ų · H-bond donors 3
XLogP
2.5
TPSA
106 Ų
H-bond donors
3
H-bond acceptors
10
Rotatable bonds
3
Heavy atoms
28

SMILES CC1=C(OC2=C1C=C(C=C2F)F)[C@H](C(F)(F)F)NC(=O)NC3=CN=C(N=C3)N

Computed descriptors from PubChem (CID 166532451), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.