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Chemical structure of EML734

GC73592

EML734

Also known as methyl 6-[3-[[N'-[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl]carbamimidoyl]amino]propylcarbamoylamino]-4-hydroxynaphthalene-2-carboxylate

EML734 is a potent and selective PRMT7/9 inhibitor with IC50 values of 315 nM and 0·89 μM, respectively

ChemicalCAS3031795-11-3MW608.61FormulaC27H32N10O7
CAS number
3031795-11-3
Molecular weight
608.61
Formula
C27H32N10O7
Solubility
DMSO ： 100 mg/mL (164·31 mM; Need ultrasonic)
InChIKey
GJPQENHVEQGHGP-UMCMBGNQSA-N
Catalogue number
GC73592
Brand
GLPBIO
Computed properties PubChem CID 162679112 · XLogP -1.1 · TPSA 257 Ų · H-bond donors 8
XLogP
-1.1
TPSA
257 Ų
H-bond donors
8
H-bond acceptors
12
Rotatable bonds
11
Heavy atoms
44

SMILES COC(=O)C1=CC(=C2C=C(C=CC2=C1)NC(=O)NCCCNC(=NC[C@@H]3[C@H]([C@H]([C@@H](O3)N4C=NC5=C(N=CN=C54)N)O)O)N)O

Computed descriptors from PubChem (CID 162679112), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.