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Chemical structure of Os30

GC73567

Os30

Also known as N-[2-[4-(dimethylamino)piperidin-1-yl]-5-[[4-(1-methylindol-3-yl)pyrimidin-2-yl]amino]phenyl]methanesulfonamide

Os30, a potent fourth-generation EGFR inhibitor, is a potent EGFRC797S-TK inhibitor with IC50 values of 18 nM and 113 nM for EGFRDel19/T790M/C797S TK and EGFRL858R/T790M/C797S TK, respectively

ChemicalCAS2998928-68-8MW519.66FormulaC27H33N7O2S
CAS number
2998928-68-8
Molecular weight
519.66
Formula
C27H33N7O2S
Solubility
DMSO ： 50 mg/mL (96·22 mM; ultrasonic and warming and heat to 80°C)
InChIKey
QBVWTVAJGQIBKK-UHFFFAOYSA-N
Catalogue number
GC73567
Brand
GLPBIO
Computed properties PubChem CID 169450221 · XLogP 3.5 · TPSA 104 Ų · H-bond donors 2
XLogP
3.5
TPSA
104 Ų
H-bond donors
2
H-bond acceptors
8
Rotatable bonds
7
Heavy atoms
37

SMILES CN1C=C(C2=CC=CC=C21)C3=NC(=NC=C3)NC4=CC(=C(C=C4)N5CCC(CC5)N(C)C)NS(=O)(=O)C

Computed descriptors from PubChem (CID 169450221), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.