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Chemical structure of CCT374705

GC73452

CCT374705

Also known as (2S)-10-[(3-chloro-2-fluoro-4-pyridinyl)amino]-2-cyclopropyl-3,3-difluoro-7-methyl-2,4-dihydro-1H-[1,4]oxazepino[2,3-c]quinolin-6-one

CCT374705 is an orally active BCL6 inhibitor with potent antiproliferative effects in vitro

ChemicalCAS2640647-90-9MW450.84FormulaC21H18ClF3N4O2
CAS number
2640647-90-9
Molecular weight
450.84
Formula
C21H18ClF3N4O2
Solubility
DMSO : 100 mg/mL (221·81 mM; Need ultrasonic)
InChIKey
MCRHRRIGPAVFNY-SFHVURJKSA-N
Catalogue number
GC73452
Brand
GLPBIO
Computed properties PubChem CID 156276733 · XLogP 4.2 · TPSA 66.5 Ų · H-bond donors 2
XLogP
4.2
TPSA
66.5 Ų
H-bond donors
2
H-bond acceptors
8
Rotatable bonds
3
Heavy atoms
31

SMILES CN1C2=C(C=C(C=C2)NC3=C(C(=NC=C3)F)Cl)C4=C(C1=O)OCC([C@@H](N4)C5CC5)(F)F

Computed descriptors from PubChem (CID 156276733), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

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Documents
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