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Chemical structure of PBRM1-BD2-IN-5

GC73351

PBRM1-BD2-IN-5

Also known as 5-chloro-2-(3-methylphenyl)-2,3-dihydro-1H-quinazolin-4-one

PBRM1-BD2-IN-5 is a potent PBRM1 Bromodomain inhibitor with Kd values of 1·5 μM and 3·9 μM for PBRM1-BD2 and PBRM1-BD5, respectively, and an IC50 value of 0·26 μM for PBRM1-BD2

ChemicalCAS2819989-61-0MW272.73FormulaC15H13ClN2O
CAS number
2819989-61-0
Molecular weight
272.73
Formula
C15H13ClN2O
Solubility
DMSO : 100 mg/mL (366·66 mM; Need ultrasonic)
InChIKey
OBDBCXGMLSMARG-UHFFFAOYSA-N
Catalogue number
GC73351
Brand
GLPBIO
Computed properties PubChem CID 164880770 · XLogP 3.6 · TPSA 41.1 Ų · H-bond donors 2
XLogP
3.6
TPSA
41.1 Ų
H-bond donors
2
H-bond acceptors
2
Rotatable bonds
1
Heavy atoms
19

SMILES CC1=CC(=CC=C1)C2NC3=C(C(=CC=C3)Cl)C(=O)N2

Computed descriptors from PubChem (CID 164880770), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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