Loading...
Chemical structure of DHFR-IN-4

GC73335

DHFR-IN-4

Also known as 5-(4-methylphenyl)-6-(morpholin-4-ylmethyl)imidazo[2,1-b][1,3]thiazole-3-carbohydrazide

DHFR-IN-4 is a potent didrofolate reductase (DHFR) inhibitor with an IC50 value of 123 nM

ChemicalCAS2820126-49-4MW371.46FormulaC18H21N5O2S
CAS number
2820126-49-4
Molecular weight
371.46
Formula
C18H21N5O2S
Solubility
DMSO ： 125 mg/mL (336·51 mM; Need ultrasonic)
InChIKey
MSIRVCGEZTUEOG-UHFFFAOYSA-N
Catalogue number
GC73335
Brand
GLPBIO
Computed properties PubChem CID 165412710 · XLogP 2.3 · TPSA 113 Ų · H-bond donors 2
XLogP
2.3
TPSA
113 Ų
H-bond donors
2
H-bond acceptors
6
Rotatable bonds
4
Heavy atoms
26

SMILES CC1=CC=C(C=C1)C2=C(N=C3N2C(=CS3)C(=O)NN)CN4CCOCC4

Computed descriptors from PubChem (CID 165412710), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.