Loading...
Chemical structure of XF067-68

GC73306

XF067-68

Also known as N-[5-[2-fluoro-5-[[2-[[(2S)-1-[(2R,4S)-4-hydroxy-2-[[(1S)-1-[4-(4-methyl-1,3-thiazol-5-yl)phenyl]ethyl]carbamoyl]pyrrolidin-1-yl]-3,3-dimethyl-1-oxobutan-2-yl]amino]-2-oxoethyl]carbamoyl]phenyl]-2-[(3R,5S)-3,4,5-trimethylpiperazin-1-yl]phenyl]-6-oxo-4-(trifluoromethyl)-1H-pyridine-3-carboxamide

XF067-68 is a PROTAC for targeted degradation of WD40 repeat domain protein 5 (WDR5) (extracted from patent WO2019246570A1)

ChemicalCAS2407452-79-1MW1030.14FormulaC52H59F4N9O7S
CAS number
2407452-79-1
Molecular weight
1030.14
Formula
C52H59F4N9O7S
Solubility
DMSO ： 2 mg/mL (1·94 mM; Need ultrasonic and warming)
InChIKey
HBHSDSLZXDASLT-QNNIUDCHSA-N
Catalogue number
GC73306
Brand
GLPBIO
Computed properties PubChem CID 164886628 · XLogP 5.5 · TPSA 234 Ų · H-bond donors 6
XLogP
5.5
TPSA
234 Ų
H-bond donors
6
H-bond acceptors
15
Rotatable bonds
14
Heavy atoms
73

SMILES C[C@@H]1CN(C[C@@H](N1C)C)C2=C(C=C(C=C2)C3=C(C=CC(=C3)C(=O)NCC(=O)N[C@H](C(=O)N4C[C@H](C[C@@H]4C(=O)N[C@@H](C)C5=CC=C(C=C5)C6=C(N=CS6)C)O)C(C)(C)C)F)NC(=O)C7=CNC(=O)C=C7C(F)(F)F

Computed descriptors from PubChem (CID 164886628), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.