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Chemical structure of THK01

GC73226

THK01

Also known as 7-hydroxy-3,13,23-triazahexacyclo[14.7.0.02,10.04,9.011,15.017,22]tricosa-1,4(9),5,7,10,15,17,19,21-nonaen-12-one

THK01 is a potent ROCK2 inhibitor with IC50 values of 5·7 and 923 nM for ROCK2 and ROCK1, respectively

ChemicalCAS2226941-26-8MW327.34FormulaC20H13N3O2
CAS number
2226941-26-8
Molecular weight
327.34
Formula
C20H13N3O2
Solubility
DMSO ： 125 mg/mL (381·87 mM; Need ultrasonic)
InChIKey
GXZFDXZCJALHRF-UHFFFAOYSA-N
Catalogue number
GC73226
Brand
GLPBIO
Computed properties PubChem CID 139589939 · XLogP 3.3 · TPSA 80.9 Ų · H-bond donors 4
XLogP
3.3
TPSA
80.9 Ų
H-bond donors
4
H-bond acceptors
2
Rotatable bonds
0
Heavy atoms
25

SMILES C1C2=C3C4=CC=CC=C4NC3=C5C(=C2C(=O)N1)C6=C(N5)C=CC(=C6)O

Computed descriptors from PubChem (CID 139589939), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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