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Chemical structure of Val-Ala-PABC-Exatecan

GC73122

Val-Ala-PABC-Exatecan

Also known as [4-[[(2S)-2-[[(2S)-2-amino-3-methylbutanoyl]amino]propanoyl]amino]phenyl]methyl N-[(10S,23S)-10-ethyl-18-fluoro-10-hydroxy-19-methyl-5,9-dioxo-8-oxa-4,15-diazahexacyclo[14.7.1.02,14.04,13.06,11.020,24]tetracosa-1,6(11),12,14,16,18,20(24)-heptaen-23-yl]carbamate

Val-Ala-PABC-Exatecan is a Drug-Linker Conjugates for ADC,consiting of a cleavable Tesirine linker (Val-Ala-PABC) and Exatecan (topoisomerase I inhibitor,)

ChemicalCAS2845164-91-0MW754.8FormulaC40H43FN6O8
CAS number
2845164-91-0
Molecular weight
754.8
Formula
C40H43FN6O8
Solubility
DMSO ： 200 mg/mL (264·97 mM; ultrasonic and warming and heat to 60°C)
InChIKey
ZACAMCPLQSLRJF-PICQSYHMSA-N
Catalogue number
GC73122
Brand
GLPBIO
Computed properties PubChem CID 168476107 · XLogP 2 · TPSA 202 Ų · H-bond donors 5
XLogP
2
TPSA
202 Ų
H-bond donors
5
H-bond acceptors
11
Rotatable bonds
10
Heavy atoms
55

SMILES CC[C@@]1(C2=C(COC1=O)C(=O)N3CC4=C5[C@H](CCC6=C5C(=CC(=C6C)F)N=C4C3=C2)NC(=O)OCC7=CC=C(C=C7)NC(=O)[C@H](C)NC(=O)[C@H](C(C)C)N)O

Computed descriptors from PubChem (CID 168476107), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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