Loading...
Chemical structure of EB1

GC73118

EB1

Also known as 4,6-diphenyl-2H-pyrazolo[3,4-b]pyridin-3-amine

EB1 is the inhibitor of kinases MNK with IC50s of 0·69 μM (MNK1) and 9·4 μM (MNK2)

ChemicalCAS42951-68-8MW286.33FormulaC18H14N4
CAS number
42951-68-8
Molecular weight
286.33
Formula
C18H14N4
Solubility
DMSO ： 8·33 mg/mL (29·09 mM; ultrasonic and warming and heat to 60°C)
InChIKey
NGNHXYCLUMQSKR-UHFFFAOYSA-N
Catalogue number
GC73118
Brand
GLPBIO
Computed properties PubChem CID 2048804 · XLogP 3.8 · TPSA 67.6 Ų · H-bond donors 2
XLogP
3.8
TPSA
67.6 Ų
H-bond donors
2
H-bond acceptors
3
Rotatable bonds
2
Heavy atoms
22

SMILES C1=CC=C(C=C1)C2=CC(=NC3=NNC(=C23)N)C4=CC=CC=C4

Computed descriptors from PubChem (CID 2048804), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.