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Chemical structure of MC-VC-PAB-NH2 TFA

GC73050

MC-VC-PAB-NH2 TFA

Also known as [4-[[(2S)-5-(carbamoylamino)-2-[[(2S)-2-[6-(2,5-dioxopyrrol-1-yl)hexanoylamino]-3-methylbutanoyl]amino]pentanoyl]amino]phenyl]methyl N-(2-aminoethyl)carbamate;2,2,2-trifluoroacetic acid

MC-VC-PAB-NH2 TFA is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)

ChemicalCAS1616727-21-9MW772.77FormulaC33H47F3N8O10
CAS number
1616727-21-9
Molecular weight
772.77
Formula
C33H47F3N8O10
Solubility
DMSO : 250 mg/mL (323·51 mM; Need ultrasonic)
InChIKey
VRAGHKSLZZJHCO-QAVRJCAVSA-N
Catalogue number
GC73050
Brand
GLPBIO
Computed properties PubChem CID 168510540 · TPSA 281 Ų · H-bond donors 8 · H-bond acceptors 14
TPSA
281 Ų
H-bond donors
8
H-bond acceptors
14
Rotatable bonds
21
Heavy atoms
54

SMILES CC(C)[C@@H](C(=O)N[C@@H](CCCNC(=O)N)C(=O)NC1=CC=C(C=C1)COC(=O)NCCN)NC(=O)CCCCCN2C(=O)C=CC2=O.C(=O)(C(F)(F)F)O

Computed descriptors from PubChem (CID 168510540), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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