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Chemical structure of AMDE-1

GC72896

AMDE-1

Also known as 2-[5,7-bis(trifluoromethyl)-1,8-naphthyridin-2-yl]-2-(3-chlorophenyl)acetonitrile

AMDE-1 is a potent autophagy inducer

ChemicalCAS478043-30-0MW415.72FormulaC18H8ClF6N3
CAS number
478043-30-0
Molecular weight
415.72
Formula
C18H8ClF6N3
Solubility
DMSO ： 100 mg/mL (240·55 mM; Need ultrasonic)
InChIKey
QPWWAOMXYPIDOY-UHFFFAOYSA-N
Catalogue number
GC72896
Brand
GLPBIO
Computed properties PubChem CID 3803930 · XLogP 5.3 · TPSA 49.6 Ų · H-bond donors 0
XLogP
5.3
TPSA
49.6 Ų
H-bond donors
0
H-bond acceptors
9
Rotatable bonds
2
Heavy atoms
28

SMILES C1=CC(=CC(=C1)Cl)C(C#N)C2=NC3=C(C=C2)C(=CC(=N3)C(F)(F)F)C(F)(F)F

Computed descriptors from PubChem (CID 3803930), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.