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Chemical structure of Sorbitol dehydrogenase-IN-1

GC72894

Sorbitol dehydrogenase-IN-1

Also known as (1R)-1-[4-[(2R,6S)-4-(4,6-dimethyl-1,3,5-triazin-2-yl)-2,6-dimethylpiperazin-1-yl]pyrimidin-2-yl]ethanol

Sorbitol dedrogenase-IN-1 is a potent and orally active sorbitol dedrogenase inhibitor with IC50 s of 4, 5 nM for rat and human, respectively

ChemicalCAS300551-49-9MW343.43FormulaC17H25N7O
CAS number
300551-49-9
Molecular weight
343.43
Formula
C17H25N7O
Solubility
DMSO ： 40 mg/mL (116·47 mM; ultrasonic and warming and heat to 60°C)
InChIKey
FTEQMUXMWCGJAF-GRYCIOLGSA-N
Catalogue number
GC72894
Brand
GLPBIO
Computed properties PubChem CID 10132209 · XLogP 1.9 · TPSA 91.2 Ų · H-bond donors 1
XLogP
1.9
TPSA
91.2 Ų
H-bond donors
1
H-bond acceptors
8
Rotatable bonds
3
Heavy atoms
25

SMILES C[C@@H]1CN(C[C@@H](N1C2=NC(=NC=C2)[C@@H](C)O)C)C3=NC(=NC(=N3)C)C

Computed descriptors from PubChem (CID 10132209), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.