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Chemical structure of (1R)-AZD-1480

GC72769

(1R)-AZD-1480

Also known as 5-chloro-2-N-[(1R)-1-(5-fluoropyrimidin-2-yl)ethyl]-4-N-(5-methyl-1H-pyrazol-3-yl)pyrimidine-2,4-diamine

(1R)-AZD-1480 is the (1R) chiral isomer of AZD-1480, an ATP competitive JAK1 and JAK2 inhibitor

ChemicalCAS935666-99-2MW348.77FormulaC14H14ClFN8
CAS number
935666-99-2
Molecular weight
348.77
Formula
C14H14ClFN8
Solubility
DMSO ： 100 mg/mL (286·72 mM; Need ultrasonic)
InChIKey
PDOQBOJDRPLBQU-MRVPVSSYSA-N
Catalogue number
GC72769
Brand
GLPBIO
Computed properties PubChem CID 53324514 · XLogP 2.4 · TPSA 104 Ų · H-bond donors 3
XLogP
2.4
TPSA
104 Ų
H-bond donors
3
H-bond acceptors
8
Rotatable bonds
5
Heavy atoms
24

SMILES CC1=CC(=NN1)NC2=NC(=NC=C2Cl)N[C@H](C)C3=NC=C(C=N3)F

Computed descriptors from PubChem (CID 53324514), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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