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Chemical structure of A3373

GC71329

A3373

Also known as N-[3,5-bis(trifluoromethyl)phenyl]-5-fluoro-1H-indole-2-carboxamide

A3373, a novel chemical inhibitor of Phospholipase D1 (PLD1) and PLD2, with IC50 of 325 nM and 15·15 μM, respectively, inhibits LPS-induced immune response and plays important roles in autoimmune arthritis, bone demineralization and osteoclastogenesis

ChemicalCAS2324948-66-3MW390.25FormulaC17H9F7N2O
CAS number
2324948-66-3
Molecular weight
390.25
Formula
C17H9F7N2O
Solubility
DMSO ： 100 mg/mL (256·25 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
InChIKey
PJRXCSGWZDFONX-UHFFFAOYSA-N
Catalogue number
GC71329
Brand
GLPBIO
Computed properties PubChem CID 170716780 · XLogP 5.1 · TPSA 44.9 Ų · H-bond donors 2
XLogP
5.1
TPSA
44.9 Ų
H-bond donors
2
H-bond acceptors
8
Rotatable bonds
2
Heavy atoms
27

SMILES C1=CC2=C(C=C1F)C=C(N2)C(=O)NC3=CC(=CC(=C3)C(F)(F)F)C(F)(F)F

Computed descriptors from PubChem (CID 170716780), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.