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Chemical structure of JM6

GC71312

JM6

Also known as 3,4-dimethoxy-N-[4-(3-nitrophenyl)-5-(piperidin-1-ylmethyl)-1,3-thiazol-2-yl]benzenesulfonamide

JM6 is a weak kynurenine 3-monooxygenase (KMO) inhibitor with an IC50 of 19·85 μM for mouse KMO

ChemicalCAS1008119-83-2MW518.61FormulaC23H26N4O6S2
CAS number
1008119-83-2
Molecular weight
518.61
Formula
C23H26N4O6S2
InChIKey
AOZLMMDVJOGGEQ-UHFFFAOYSA-N
Catalogue number
GC71312
Brand
GLPBIO
Computed properties PubChem CID 24812126 · XLogP 4 · TPSA 163 Ų · H-bond donors 1
XLogP
4
TPSA
163 Ų
H-bond donors
1
H-bond acceptors
10
Rotatable bonds
8
Heavy atoms
35

SMILES COC1=C(C=C(C=C1)S(=O)(=O)NC2=NC(=C(S2)CN3CCCCC3)C4=CC(=CC=C4)[N+](=O)[O-])OC

Computed descriptors from PubChem (CID 24812126), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

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Documents
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