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Chemical structure of PKR activator 4

GC71235

PKR activator 4

Also known as 7-methyl-4-[[1-(2-trimethylsilylethoxymethyl)pyrazol-3-yl]methyl]-3-thia-5,7,10,11-tetrazatricyclo[6.4.0.02,6]dodeca-1(8),2(6),4,11-tetraen-9-one

PKR activator 4 (example 7A) is a potent pyruvate kinase R (PKR) activator

ChemicalCAS2283420-05-1MW416.57FormulaC18H24N6O2SSi
CAS number
2283420-05-1
Molecular weight
416.57
Formula
C18H24N6O2SSi
Solubility
DMSO ： 50 mg/mL (120·03 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
InChIKey
OJINPWVFOQGLEV-UHFFFAOYSA-N
Catalogue number
GC71235
Brand
GLPBIO
Computed properties PubChem CID 151335432 · TPSA 115 Ų · H-bond donors 1 · H-bond acceptors 6
TPSA
115 Ų
H-bond donors
1
H-bond acceptors
6
Rotatable bonds
7
Heavy atoms
28

SMILES CN1C2=C(C=NNC2=O)C3=C1N=C(S3)CC4=NN(C=C4)COCC[Si](C)(C)C

Computed descriptors from PubChem (CID 151335432), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.