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Chemical structure of MTK458

GC71210

MTK458

Also known as N-[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]-6-(trifluoromethyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine

MTK458 is an orally active brain penetrant PINK1 activator

ChemicalCAS2499962-58-0MW332.32FormulaC17H15F3N4
CAS number
2499962-58-0
Molecular weight
332.32
Formula
C17H15F3N4
Solubility
DMSO ： 100 mg/mL (300·91 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
InChIKey
JOIONRWKOGDQOG-CYBMUJFWSA-N
Catalogue number
GC71210
Brand
GLPBIO
Computed properties PubChem CID 155187445 · XLogP 4.2 · TPSA 53.6 Ų · H-bond donors 2
XLogP
4.2
TPSA
53.6 Ų
H-bond donors
2
H-bond acceptors
6
Rotatable bonds
2
Heavy atoms
24

SMILES C1C[C@H](C2=CC=CC=C2C1)NC3=NC=NC4=C3C=C(N4)C(F)(F)F

Computed descriptors from PubChem (CID 155187445), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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