Loading...
Chemical structure of STING-IN-5

GC71189

STING-IN-5

Also known as benzyl (2E)-2-[(3R,4S,5S,8S,9S,10S,11R,13R,14S,16S)-16-acetyloxy-11-hydroxy-4,8,10,14-tetramethyl-3-[3-[[3-oxo-3-(prop-2-enoxyamino)propyl]disulfanyl]propanoyloxy]-2,3,4,5,6,7,9,11,12,13,15,16-dodecahydro-1H-cyclopenta[a]phenanthren-17-ylidene]-6-methylhept-5-enoate

STING-IN-5 is a potent STING inhibitor, inhibiting LPS-induced NO synthesis in macrophages with an IC50 value of 1·15 μM

ChemicalCAS2920064-17-9MW854.17FormulaC47H67NO9S2
CAS number
2920064-17-9
Molecular weight
854.17
Formula
C47H67NO9S2
Solubility
DMSO ： 100 mg/mL (117·07 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
InChIKey
UBXHZHGRHRYYRQ-KBRRQLEJSA-N
Catalogue number
GC71189
Brand
GLPBIO
Computed properties PubChem CID 171702717 · XLogP 8.5 · TPSA 188 Ų · H-bond donors 2
XLogP
8.5
TPSA
188 Ų
H-bond donors
2
H-bond acceptors
11
Rotatable bonds
21
Heavy atoms
59

SMILES C[C@H]1[C@@H]2CC[C@]3([C@H]([C@]2(CC[C@H]1OC(=O)CCSSCCC(=O)NOCC=C)C)[C@@H](C[C@@H]\4[C@@]3(C[C@@H](/C4=C(\CCC=C(C)C)/C(=O)OCC5=CC=CC=C5)OC(=O)C)C)O)C

Computed descriptors from PubChem (CID 171702717), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.